The latest SAGE Crossroads webcast features Mike Treder of the Center for Responsible Nanotechnology in a discussion of nanotechnology as it applies to aging and longevity research. In fact the webcast touches on a wide variety of associated topics, with the normal mix of conservatism and forward thinking from all sides. Individual attitudes towards change are certainly interesting to examine. The CRN folks worry about a number of social issues that are, in my opinion, not things we need to worry about at all - but it's good to have people thinking about the future of nanotechnology. Entities like CRN and the Foresight Institute play an important part in the march towards working nanomedicine.