We already know that cancer and aging share, effect and stem from many of the same biochemical and cellular processes. Now it appears that there may also be a significant overlap between stem cell repair and cancer mechanisms. "There is growing evidence that stem cells gone awry in their efforts to repair tissue damage could help explain why long-term irritation, such as from alcohol or heartburn, can create a breeding ground for certain cancers. ... If these stem cells are the starting point of some cancers, multiple genetic and other changes may be required to trap the stem cell during chronic irritation, and perhaps many more changes to get the rapid growth of cancer. We need to figure out what those changes might be."