The Evidence For Calorie Restriction

SignOnSanDiego takes a look at some of the science backing calorie restriction as the only currently available way of even modestly extending healthy human life span. "A human study by John O. Holloszy, a professor of medicine at Washington University in St. Louis, published earlier this year noted that 18 people who had been practicing CR for three to 15 years showed dramatically reduced risk of developing diabetes or clogged arteries.
... It's very clear that calorie restriction has a powerful, protective effect against diseases associated with aging ... We don't know how long each individual actually will end up living, but they certainly have a much longer life expectancy than average because they're most likely not going to die from a heart attack, stroke or diabetes."

Link: http://www.signonsandiego.com/news/science/20041124-9999-lz1c24cr.html