Betterhumans is printing a very helpful piece on Lifeline and Protandim - a new anti-oxidant regulator with nice lab work from Ceremedix (as CMX-1152) behind it. This article goes in depth on the science and the uncertainty; it's not even entirely clear that what is currently branded as Protandim is the same substance as CMX-1152. While I'm sure that Protandim will be well-received by the healthy life extension community (as was resveratrol), it is simply too early to say whether this pill will have any meaningful benefits. The recent history of supplements is littered with substances that did well in the lab, but do nothing when ingested as pills, or whose supposed benefits were later invalidated. Make your own risk-reward calculation for Protandim, but make it an educated choice.