A new study offers the following conclusions: "Restricting the diets of mice reduces the build-up of plaques in the brain that are linked to Alzheimer's disease, according to a new study that offers further evidence of the benefits of calorie restriction. Obese people are already considered to be at a higher risk for developing Alzheimer's but the findings offer some insight into a possible explanation for this trend." The normal cautions apply to extrapolating work on mice to humans, but researchers suspect that lowered blood glucose and insulin are good places to look for an explanation of this calorie restriction benefit. Isn't it time that you investigated calorie restriction? The health benefits are legion and its the only proven, available way to even modestly extend healthy life span.