Betterhumans has been rolling out the good articles of late. Here, we have a possible biochemical explanation for some longevity benefits of exercise: "Perhaps some of the beneficial effects of exercise in human health are the result of the effect of AMP-1 activation on the aging process ... researchers found that by giving extra copies of the enzyme to nematode worms, the worms lived an average of 13% longer than controls. They also report that environmental stressors that activate the enzyme extend lifespan. ... This work supports our premise that aging is highly regulated and extends our list of molecular targets in pathways that affect lifespan by controlling metabolic processes." The work is from Elixir Pharmaceuticals, one of the companies currently pushing the aging research envelope.