Embryonic Stem Cell Progress

(From ScienceDaily). By applying new techniques to control embryonic stem (ES) cell differentiation, researchers have succeeded in reversing hemophilia - a genetic defect of the liver - in mice. "In the study, ES cells were treated with fibroblast growth factor for seven days prior to injection. As expected, this resulted in ES cells differentiating into early endoderm like precursors, which the researchers named 'putative endoderm precursors,' or PEPs. Endoderm refers to the inner layer of early embryonic cells that develops into the digestive and respiratory systems. Not only do ES cells differentiate into PEPs, they also engraft, persist, differentiate further and then function following injection ... the PEP cells robustly engraft within the liver and were not recognized by the immune system as foreign."

Link: http://www.sciencedaily.com/releases/2005/02/050222194021.htm

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