Latest Ellison Foundation Grants

One of the most recent grants provided by the Ellison Medical Foundation went to biologist Alexander Varshavsky "to conduct a systematic investigation of the genetics and biochemistry of aging. ... Every cell contains within it a molecular machine to eventually destroy its own proteins, he notes ... Detailed understanding of these protein-destruction pathways will have a profound impact on the practice of medicine, because all kinds of things that go wrong with us, from cancer and infectious diseases, to neurodegenerative syndromes and even normal aging, have a lot to do with either inherent imperfections of the ubiquitin system, or with an overt damage to it in a specific disease ... His aim is to discover the molecular circuits that contribute to normal aging, and also to see whether some of the alterations that he plans to introduce could slow down the aging process."


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