Always More Complex Than You Think

Here's a little something from PubMed for those who like to keep tabs on telomere research and its application to healthy life extension: "We examined telomere biology in rabbits to expand the comparative biology of telomere-directed replicative senescence within mammals. ... The leporids neither exhibited cellular senescence after sustained periods in culture nor displayed detectable telomerase activity. Continued culture was possible because of their extremely long telomeric arrays. Immunofluorescence showed robust telomere signals at chromosome ends and significant internal chromosomal staining in some instances. ... These results show that it is unlikely that lagomorphs use telomere shortening and replicative senescence as a tumor protective mechanism.



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