Fishing For Alzheimer's Drugs

While scientists use the tools of modern biotechnology to uncover the mechanisms of Alzheimer's disease, another path forward lies in low-cost mass analysis of potential drugs. Bioinformatics and new tools have made the process of screening potential compounds comparatively cheap - and the cost is still falling. Here, EurekAlert reports that a "team of scientists has discovered three molecules - from a search of 58,000 compounds - that appear to inhibit a key perpetrator of Alzheimer's disease.
Each of the three molecules protects the protein called 'tau,' which becomes hopelessly tangled in the brains of patients with Alzheimer's. The finding is promising news for the development of drugs for the disease." You may recall recent promising work on tau and neurofibrillary tangles in Alzheimer's.

Link: http://www.eurekalert.org/pub_releases/2005-07/uoc--sdt072005.php

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