People expend a great deal of energy attempting to obtain health benefits based on studies demonstrating correlations between aspects of diet, lifestyle and health. Determining underlying biochemical mechanisms is a step beyond, however - it brings precise therapies and explanations for variations in effectiveness of the old strategies. Here, EurekAlert reports on new understanding of some cancer-protective compounds: "Compounds like sulforaphane in broccoli and resveratrol in wine have been shown to prevent cancer. They do that by signaling our bodies to ramp up the production of proteins capable of preventing damage to our DNA. We now have a good idea how that signal works."