Understanding A Tumor Suppression Gene

It should be fairly clear from the past decade of research that understanding the underlying biochemistry of disease leads to targeted, effective therapies. From EurekAlert: "A critical event in the development of melanoma and other human cancers is the inactivation of a gene known as 'p16.' Normally, p16 keeps cells from growing rapidly, a condition that sometimes leads to tumor formation. ... The p16 gene works by producing a protein that attaches to [key growth-promotion enzymes], preventing them from performing their function. When the researchers added the p16 protein to colonies of cancer cells in culture, it diminished the size of many colonies, wiping out some of them. It also decreased the total number of cancer cells."

Link: http://www.eurekalert.org/pub_releases/2005-07/uom-rdh070705.php

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