Shedding Light On DNA Repair

If we fully understand how our cells repair damaged DNA, then we should be able to find ways to improve on the process in order to prevent age-related degeneration caused by accumulated DNA damage. Here, EurekAlert reports on another step forward towards this understanding: "researchers have discovered a new gene, FANCM, which sheds light on an important pathway involved in the repair of damaged DNA. Specifically, mutation in this gene is responsible for one of the forms of Fanconi anemia (FA) ... understanding this gene's role in the development of FA provides insights into other medical problems - in this case, age-related conditions ... We believe that this new gene, FANCM, may be a potent cog in the DNA repair machinery. It is possible that we could learn how to promote the function of DNA repair complexes and thereby prevent the age-related accumulation of DNA damage."



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