Protofection At SENS 2

Kevin Perrott of Health Extension reports on biologist Rafal Smigrodzki's presentation on mitochondrial protofection at SENS 2: "It has become apparent that more than 90% of our [mitochondrial DNA] is mutated by adult life. He proposes that the mutation burden of mitochondria, although specific species may comprise less than 3% each, together combine to cause age related disease and point an even sharper finger at mitochondrial degneration as the main culprit in the aging process. ... If wholesale mitochondrial gene therapy becomes available AND [mutational damage to mitochondrial DNA] indeed turns out to be critical to the aging process, it is possible that this may be one of the most significant discoveries yet in biogerontology."



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