Why CR Would Work For Human Longevity
The latest issue of Biogerontology contains a number of articles on calorie restriction (CR), reflecting the spectrum of positions with regard to its likely effects on human longevity. From the optimistic side of the fence: "To delineate the cellular and molecular mechanisms of CR's efficacy on human longevity, this review elaborates on the modulation of CR on the inflammatory process, a common risk factor for many chronic diseases. Discussions also include evidence from human data on the effect of CR in the loss of body weight, known to suppress inflammatory cytokines, subsequently leading to the reduction of chronic diseases known to compromise the functional longevity of humans." The strongly positive effects on human health have been handily demonstrated in recent years - you owe it to yourself to look into calorie restriction.
Link: http://www.springerlink.com/openurl.asp?genre=article&id=doi:10.1007/s10522-006-9009-y