Turning Off Cellular Senescence

Chemical & Engineering News offers more insight into recent Korean research relating to the manipulation of cellular senescence: "Korean researchers have found a complex thiourea derivative that can extend the lifetime of mammalian cells and reverse cellular aging. ... CGK733 was discovered by screening a library of 20,000 synthetic molecules for their effects on aging cells ... CGK733 is an example of what many scientists hope will be a trend: the identification of small molecules to mimic more cumbersome genetic interventions to regulate cellular behavior." Cellular senescence has little to do with the common meaning of the term "senescence" in relation to degenerative aging. A longer examination of this research and its significance can be found at Fight Aging!

Link: http://pubs.acs.org/cen/news/84/i25/8425notw4.html

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