Calories, SIRT1 and Alzheimer’s

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ScienCentral follows up on research into calorie restriction and neurodegeneration: "Calorie-restriction - consuming 30-percent fewer calories than normal - is the only scientifically proven way to slow the process of aging in organisms ranging from yeast to mammals. Now a new study in mice shows that through a similar mechanism, calorie restriction may also slow or prevent Alzheimer's disease. ... With this kind of calorie restriction we were able to improve memory function - I would say five-fold times more efficient ... Excitingly, we have been able to demonstrate that just the SIRT1 molecule, once re-introduced into brain cells was capable to recapitulate almost the same identical features of calorie restriction ... Through the regulation of SIRT1, we might be in a position to cure the disease."

Link: http://www.sciencentral.com/articles/view.php3?type=article&article_id=218392836