Anne C. makes a good point on those who object to radical life extension by claiming boredom: "The plasticity of the human brain with regard to what it finds meaningful has already been conclusively demonstrated: depressed people often find 'everyday activities' unfulfilling and then find these activities fulfilling again following pharmacological treatment. Yet the treated and untreated individual are the same person: usually, even the depressed individual has a sense that things could 'seem' subjectively fulfilling or meaningful, and this can be a motivation for treatment. If a very long-lived person becomes bored, they could presumably [seek] treatment in the same manner as a present-day depressed person might. That is, when given the choice between a treatment that could help them find meaning in things again, and eternal nonexistence / oblivion, would most people honestly choose the eternal oblivion?" Some people are more prone to boredom than others; some people enjoy life more than others. There is always the choice not to live, or to seek change so as to live better.