Decoying AGEs
An interesting idea in a review paper from earlier this year: "The receptor for advanced glycation end products (RAGE) is a cell-bound receptor of the immunoglobulin superfamily which may be activated by a variety of [advanced glycation end products or AGEs] ... soluble RAGE (sRAGE) [lacks] the transmembrane domain and therefore circulates in plasma. By competing with cell-surface RAGE for ligand binding, sRAGE may contribute to the removal/neutralization of circulating ligands thus functioning as a decoy. Clinical studies have recently shown that higher plasma levels of sRAGE are associated with a reduced risk of coronary artery disease, hypertension, the metabolic syndrome, arthritis and Alzheimer's disease." If AGEs are binding to sRAGE instead of damaging your cells, this might just be a good thing - but not as good as getting rid of the AGEs in the first place.