Telomeres and Osteoarthritis

From ScienceDaily, news of a correlation between osteoarthritis and shortened telomeres: "X-rays of both hands were taken of all participants to check for signs of osteoarthritis and a blood sample was taken to assess 'biological aging' in white cell DNA. ... Unsurprisingly, the findings showed that white cell telomere lengths were associated with chronological age. The older a person was, the shorter they were. But among the 160 people with hand osteoarthritis, the telomere length was significantly shorter than among those without the disease ... the amount of telomere shortening was equivalent to that accrued over 11 years in healthy people ... The more severe the disease, the shorter was the telomere length. ... The authors suggest that both the aging process and osteoarthritis share biological factors in common, including oxidative stress and low level chronic inflammation."



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