More On DNA Repair and Aging

Scientific American has an article on recent DNA repair research that is more clear on the point being made the scientists involved: "Do we get old due to the accumulation of damage over our lifetimes or due to the genetic blueprint we inherit? ... What we say is [that] both are valid and that, in particular, damage to DNA contributes to aging. Damage accumulates ... but it is modulated by your genetic makeup. If you have better repair and/or slower metabolism, you age slower. ... If we would be able to reduce the induction of DNA damage by triggering the survival response [to lower metabolism and allow less damage] or by boosting repair or, perhaps, by adding protecting compounds in food or medication the rate of DNA damage and consequently aging may be reduced."



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