Comments from researcher David Sinclair in this Boston Globe article: "Aging is the worst thing that has ever been put upon humanity. When I was 3 years old, I was horrified by the idea that my grandparents would die, and then my parents would die. And then one day I would die. ... I've been working without break for 11 years on this because I realize that it has the potential to revolutionize medicine. ... Cancer, heart disease, diabetes, cataracts, Alzheimer's. We aim to treat diseases of aging with a single pill. I want to see 90-year-olds play squash with their grandchildren. ... We've come farther than I ever thought we would in my lifetime." More scientists like this, please; I can't say I think the path of metabolic manipulation stands as the best foot forward towards greatly extended healthy life spans - but there can never be too many people thinking the way Sinclair does about aging and the need for action.