Ceramide and Type 2 Diabetes

ScienceDaily look at another step towards controlling age-related diabetes through medical science: researchers have "identified a common link between multiple assaults on the body, including saturated fats, obesity, and certain types of drugs, all of which can lead to insulin resistance. The researchers found that these metabolic stresses lead to an upswing in production of a particular kind of fat molecule, known as ceramide. ... We've found that ceramide has a big effect on insulin resistance. In some animal models, ceramide inhibition led to an almost complete restoration of insulin sensitivity. ... Insulin hormone stimulates the uptake and storage of blood sugar and other nutrients in skeletal muscle and fat tissue while simultaneously blocking the release of blood sugar stored in the liver ... Insulin resistance occurs when a normal dose of the hormone becomes incapable of eliciting those responses. The condition is a characteristic of or risk factor for many metabolic diseases, including diabetes, hypertension, atherosclerosis, and cancer." Exercise and losing the excess fat have demonstrated merits to the same level or better than new therapies - something to remember as you move through life. The health basics pay dividends.

Link: http://www.sciencedaily.com/releases/2007/03/070307075807.htm

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