More Science From the Edmonton Aging Symposium
Over at the Methuselah Foundation blog, LysoSENS researcher John Schloendorn provides a report on the recent Edmonton Aging Symposium: "Progress has been solid and steady in the other fields pertaining to the removal of age-related damage according to the SENS proposals: Too few cells, and too many cells, and the three types of junk (inside cells, between cells and protein crosslinks). The cellular work featured Conboy and Conboy from Berkeley, pioneers in investigating the role of how an aged bodily environment dictates the aging various stem cell types, and presented excellent data with implications on how one might go about shielding the stem cells from this influence. This might one day allow the stem cells in an aged person to ignore the body's calls to stop regenerating ... Judith Campisi [attempted] to get rid of unwanted cells [and] reported on overcoming matrix metalloproteinases, an important mechanism by which such senescent cells can defend themselves against immune cells attempting to clear them out. ... In the field of age-related storage diseases, atherosclerosis researcher Jay Jerome explained the need for enzyme therapies to resolve arterial plaques, and Rittmann showed how his Methuselah Foundation-funded work to clone suitable enzymes from environmental microbes has made excellent progress over the past year."
Link: http://blog.methuselahfoundation.org/2007/04/john_schloendorn_reports_on_th_1.html