Telomolecular Aims at Mitochondrial Repair

This is most interesting: "Telomolecular Corporation [recently] acquired a new technology from Stanford Leland Jr. University. The technology, called Mitofusin 1, allows for the repair of damaged mitochondrial DNA. Damage to mitochondrial DNA leads to forms of aging and a variety of diseases. By combining this tool with other portfolio products Telomolecular hopes to reverse certain symptoms and signs of human aging. ... The correction of damaged mitochondrial DNA may have applications in human aging. An unfortunate side effect of aerobic respiration in mitochondria is that unstable molecules called reactive oxygen species (ROS) begin to accumulate in the mitochondrial DNA compartment and cause damage to mitochondrial DNA. The intentional mutation of mitochondrial DNA in lab animals causes premature aging ... Additionally, mitochondrial DNA mutations are found to accumulate with age in humans." Telomolecular has been focused on working with telomeres in the recent past, but is now joining a select few groups aiming to block the mechanisms of the mitochondrial free radical theory of aging.

Link: http://www.checkbiotech.org/orphan_News_treatmentandhealth.aspx?infoId=401

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