Cartilage From Embryonic Stem Cells

EurekAlert! reports on continued progress in generating new cartilage to replace damaged or age-worn tissue: "Because native cartilage is unable to heal itself, researchers have long looked for ways to grow replacement cartilage in the lab that could be used to surgically repair injuries. This research offers a novel approach for producing cartilage-like cells from embryonic stem cells ... Using a series of stimuli, the researchers developed a method of converting the stem cells into cartilage cells. Building upon this work, the researchers then developed a process for using the cartilage cells to make cartilage tissue. The results show that cartilages can be generated that mimic the different types of cartilage found in the human body, such as hyaline articular cartilage -- the type of cartilage found in all joints -- and fibrocartilage -- a type found in the knee meniscus and the jaw joint. Athanasiou said the results are exciting, as they suggest that similar methods may be used to convert the stem cell-derived cartilage cells into robust cartilage sections that can be of clinical usefulness."

Link: http://www.eurekalert.org/pub_releases/2007-09/ru-esc090607.php

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