Bone From Embryonic Stem Cells

A glance at ongoing progress in control over cells and tissue via ScienceDaily: researchers "break new ground by successfully creating bone tissue 'in vivo', using embryonic stem cells. They imitated bone formation in embryos and children, which uses cartilage as a template. ... While searching for a suitable scaffold to use for cartilage tissue engineering with mouse embryonic stem cells, the researchers selected a ceramic material that is often used as bone void filler. Other materials appeared to be unsuitable or they made it difficult to locate the implanted cells. In the lab, mouse embryonic stem cells were seeded onto this ceramic material and induced into the developmental pathway leading to cartilage formation. ... a scaffold with cells that had already formed cartilage, was implanted into a rat with a defect in its skull. Besides under the skin, bone was also formed in this bone defect. Therefore, this approach seems to be a promising new technique for repairing damaged bone."

Link: http://www.sciencedaily.com/releases/2008/05/080514091744.htm

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