Long-Lived Species and Aging

From Maria Konovalenko: "There are many studies that involve extending the lives of laboratory animals - through gene manipulation, pharmaceutical intervention, and dietary restriction. But according to Steven Austad, a biologist at the Barshop Institute for Longevity and Aging Studies, these manipulations 'pale in comparison to the remarkable diversity of lifespan produced by evolution.' He points out that maximum life span across the animal kingdom varies 40,000-fold. For example, some adult flies live less than an hour; some shellfish for centuries. Among mammals alone, longevity varies 1,000-fold. The average fruit fly lives a little more than a month, so scientists' ability to double its lifespan is a remarkable achievement but Austad says we may be missing something by focusing so much of our longevity research on animals - flies, worms, mice - that are 'demonstrably unsuccessful at combating basic aging processes.' He suggests we put more effort into understanding molecular solutions nature has devised to help long-living creatures evade their deaths. ... Aging affects all of us. People are going to continue to live longer because of medical advances. We want them to live healthier as well as live longer. The best way to achieve longer health is to figure out ways to medically slow aging. That's a different sort of approach than figuring out how to cure cancer or heart disease. If you can cure aging, or if you can slow it, then you can really delay or prevent a whole host of disabilities and diseases."

Link: http://mariakonovalenko.wordpress.com/2010/11/21/what-old-animals-can-teach-us-about-aging/

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