An Example of Scaffolds to Encourage Bone Regrowth

The use of nanoscale-featured scaffold materials is common in regenerative medicine research. Here is an example that can be used to improve and guide the regrowth of bone:

Artificial bone, created using stem cells and a new lightweight plastic, could soon be used to heal shattered limbs. Researchers have developed the material with a honeycomb scaffold structure that allows blood to flow through it, enabling stem cells from the patient's bone marrow to attach to the material and grow new bone. Over time, the plastic slowly degrades as the implant is replaced by newly grown bone.

Scientists developed the material by blending three types of plastics. They used a pioneering technique to blend and test hundreds of combinations of plastics, to identify a blend that was robust, lightweight, and able to support bone stem cells. Successful results have been shown in the lab and in animal testing with the focus now moving towards human clinical evaluation.

"We were able to make and look at a hundreds of candidate materials and rapidly whittle these down to one which is strong enough to replace bone and is also a suitable surface upon which to grow new bone. We are confident that this material could soon be helping to improve the quality of life for patients with severe bone injuries, and will help maintain the health of an ageing population."

Link: http://www.southampton.ac.uk/mediacentre/news/2013/feb/13_26.shtml

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